C 264

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H534984

CAS#: 6237-22-5

Description: C 264 is a bioactive chemical.


Chemical Structure

img
C 264
CAS# 6237-22-5

Theoretical Analysis

Hodoodo Cat#: H534984
Name: C 264
CAS#: 6237-22-5
Chemical Formula: C18H20N4O2
Exact Mass: 324.16
Molecular Weight: 324.384
Elemental Analysis: C, 66.65; H, 6.21; N, 17.27; O, 9.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: C 264; C-264; C264

IUPAC/Chemical Name: 1,3-Propanediamine, N,N-dimethyl-N'-(2-nitro-9-acridinyl)- (9CI)

InChi Key: YBGPLGCFHRTAJZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H20N4O2/c1-21(2)11-5-10-19-18-14-6-3-4-7-16(14)20-17-9-8-13(22(23)24)12-15(17)18/h3-4,6-9,12H,5,10-11H2,1-2H3,(H,19,20)

SMILES Code: O=[N+](C1=CC2=C(NCCCN(C)C)C3=CC=CC=C3N=C2C=C1)[O-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 324.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: He XP, Xia JH, Wang CM, Pang HY, Yue GH. Significant associations of polymorphisms in the prolactin gene with growth traits in Asian seabass (Lates calcarifer). Anim Genet. 2012 Apr;43(2):233-6. doi: 10.1111/j.1365-2052.2011.02230.x. Epub 2011 Jul 21. PMID: 22404362.


2: Wilkinson SG, Rex MC. Structural studies of the O-specific polysaccharide from Serratia marcescens N.C.T.C. 1377. Carbohydr Res. 1983 Jan 16;112(1):95-103. doi: 10.1016/0008-6215(83)88269-x. PMID: 6339054.


3: Zhang WX , Li Y , Jin H , She YC . Two-dimensional transition-metal halide CoBr3 with spin-polarized Dirac cone. Phys Chem Chem Phys. 2019 Aug 28;21(32):17740-17745. doi: 10.1039/c9cp03337h. Epub 2019 Aug 1. PMID: 31367721.


4: Karolak JA, Polakowski P, Szaflik J, Szaflik JP, Gajecka M. Molecular Screening of Keratoconus Susceptibility Sequence Variants in VSX1, TGFBI, DOCK9, STK24, and IPO5 Genes in Polish Patients and Novel TGFBI Variant Identification. Ophthalmic Genet. 2016;37(1):37-43. doi: 10.3109/13816810.2014.926375. Epub 2014 Jun 18. Erratum in: Ophthalmic Genet. 2016;37(1):43. PMID: 24940934.


5: Wang Z, Lin L, Yuan Y, Song S. [Three novel splicing mutations at 5' terminal of DMD gene corresponding to different phenotypes]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2019 Jul 10;36(7):666-671. Chinese. doi: 10.3760/cma.j.issn.1003-9406.2019.07.003. PMID: 31302907.


6: Yang J, Liu WQ, Li WL, Chen C, Zhu Z, Hong M, Wang ZQ, Dong J. Investigating polymorphisms by bioinformatics is a potential cost-effective method to screen for germline mutations in Chinese familial adenomatous polyposis patients. Oncol Lett. 2016 Jul;12(1):421-428. doi: 10.3892/ol.2016.4646. Epub 2016 May 30. PMID: 27347161; PMCID: PMC4907044.


7: Tanojo H, Bouwstra JA, Junginger HE, Boddé HE. Subzero thermal analysis of human stratum corneum. Pharm Res. 1994 Nov;11(11):1610-6. doi: 10.1023/a:1018965906027. PMID: 7870679.


8: da Silva AS, Dias LD, Borges JF, Markoski MM, de Souza MS, Irigoyen MC, Machado UF, Schaan BD. Renal GLUT1 reduction depends on angiotensin-converting enzyme inhibition in diabetic hypertensive rats. Life Sci. 2013 Jul 10;92(24-26):1174-9. doi: 10.1016/j.lfs.2013.05.001. Epub 2013 May 13. PMID: 23680377.


9: Hellebrekers DMEI, Sallevelt SCEH, Theunissen TEJ, Hendrickx ATM, Gottschalk RW, Hoeijmakers JGJ, Habets DD, Bierau J, Schoonderwoerd KG, Smeets HJM. Novel SLC25A32 mutation in a patient with a severe neuromuscular phenotype. Eur J Hum Genet. 2017 Jun;25(7):886-888. doi: 10.1038/ejhg.2017.62. Epub 2017 Apr 26. PMID: 28443623; PMCID: PMC5520074.


10: Goldstein JA, Hoff KVS, Hillyard SD. The effect of temperature on development and behaviour of relict leopard frog tadpoles. Conserv Physiol. 2017 Feb 14;5(1):cow075. doi: 10.1093/conphys/cow075. PMID: 28421137; PMCID: PMC5388300.


11: Ding S, Zhou R, Zhu Y. Crystallization and preliminary crystallographic analysis of the chimeric protein LKB1-14-3-3ζ. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1371-3. doi: 10.1107/S1744309113029230. Epub 2013 Nov 29. PMID: 24316833; PMCID: PMC3855723.


12: Sultana A, Alexeev I, Kursula I, Mäntsälä P, Niemi J, Schneider G. Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning. Acta Crystallogr D Biol Crystallogr. 2007 Feb;63(Pt 2):149-59. doi: 10.1107/S0907444906044271. Epub 2007 Jan 16. PMID: 17242508.


13: Akizawa Y, Miyashita T, Sasaki R, Nagata R, Aoki R, Ishitani K, Nagashima Y, Matsui H, Saito K. Gorlin syndrome with an ovarian leiomyoma associated with a PTCH1 second hit. Am J Med Genet A. 2016 Apr;170A(4):1029-34. doi: 10.1002/ajmg.a.37517. Epub 2016 Jan 18. PMID: 26782978.


14: Masunaga T, Niizeki H, Yasuda F, Yoshida K, Amagai M, Ishiko A. Splicing abnormality of integrin β4 gene (ITGB4) due to nucleotide substitutions far from splice site underlies pyloric atresia-junctional epidermolysis bullosa syndrome. J Dermatol Sci. 2015 Apr;78(1):61-6. doi: 10.1016/j.jdermsci.2015.01.016. Epub 2015 Feb 7. PMID: 25728941.


15: Martorana D, Neri TM. TNF receptor-associated periodic fever syndrome caused by sequence alterations in exonic splicing enhancers: comment on the article by Trübenbach et al. Rheumatol Int. 2010 Jul;30(9):1269-71. doi: 10.1007/s00296-009-1167-1. Epub 2009 Oct 13. PMID: 19823838.


16: Vallazza M, Perbandt M, Klussmann S, Rypniewski W, Einspahr HM, Erdmann VA, Betzel Ch. First look at RNA in L-configuration. Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):1-7. doi: 10.1107/s0907444903027690. Epub 2003 Dec 18. PMID: 14684885.


17: Sakamoto M, Kouhei D, Haniffa M, Silva S, Troncoso M, Santander P, Schonstedt V, Stecher X, Okamoto N, Hamanaka K, Mizuguchi T, Mitsuhashi S, Miyake N, Matsumoto N. A novel ITPA variant causes epileptic encephalopathy with multiple-organ dysfunction. J Hum Genet. 2020 May 14. doi: 10.1038/s10038-020-0765-3. Epub ahead of print. PMID: 32405030.


18: Ou D, Mitchell LA, Décarie D, Gillam S, Tingle AJ. Characterization of an overlapping CD8+ and CD4+ T-cell epitope on rubella capsid protein. Virology. 1997 Sep 1;235(2):286-92. doi: 10.1006/viro.1997.8704. PMID: 9281508.


19: Sasaki R, Miyashita T, Matsumoto N, Fujii K, Saito K, Ando T. Multiple keratocystic odontogenic tumors associated with nevoid basal cell carcinoma syndrome having distinct PTCH1 mutations: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug;110(2):e41-6. doi: 10.1016/j.tripleo.2010.04.006. PMID: 20659694.


20: Kapoor RR, Locke J, Colclough K, Wales J, Conn JJ, Hattersley AT, Ellard S, Hussain K. Persistent hyperinsulinemic hypoglycemia and maturity-onset diabetes of the young due to heterozygous HNF4A mutations. Diabetes. 2008 Jun;57(6):1659-63. doi: 10.2337/db07-1657. Epub 2008 Feb 11. PMID: 18268044.