WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H555818
CAS#: 181147-28-4 (HCl)
Description: YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity. YCN47284 was first reported in WO 9621450. YCN47284 inhibited P. falciparum growth with IC50 = 0.075 μM to >10 μM as reported in US 20030186993. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
Hodoodo Cat#: H555818
Name: YCN47284
CAS#: 181147-28-4 (HCl)
Chemical Formula: C10H16Cl2N8
Exact Mass: 246.13
Molecular Weight: 319.190
Elemental Analysis: C, 37.63; H, 5.05; Cl, 22.21; N, 35.11
Related CAS #: 181147-28-4 (HCl) 81913-34-0 (free base)
Synonym: YCN47284; YCN-47284; YCN 47284;
IUPAC/Chemical Name: Hydrazinecarboximidamide, 2,2'-(1,3-phenylenedimethylidyne)bis-, dihydrochloride
InChi Key: YZGIIAFNMJQKRC-CLEIDKRQSA-N
InChi Code: InChI=1S/C10H14N8.2ClH/c11-9(12)17-15-5-7-2-1-3-8(4-7)6-16-18-10(13)14;;/h1-6H,(H4,11,12,17)(H4,13,14,18);2*1H/b15-5+,16-6+;;
SMILES Code: N/C(N)=N\N=C\C1=CC=CC(/C=N/N=C(N)/N)=C1.[H]Cl.[H]Cl
Appearance: Red semisolid or visicous liquid
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 319.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
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| In vivo protocol: |
