WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H575249
CAS#: 186835-06-3
Description: F-050 is a biochemical that has been shown to inhibit platelet aggregation induced by CaCl2, arachidonic acid, collagen, adenosine diphosphate (ADP) and thrombin in guinea pigs, rabbits and rats in vitro. F-050 may be useful in the treatment of thrombotic diseases.
Hodoodo Cat#: H575249
Name: F-050
CAS#: 186835-06-3
Chemical Formula: C21H20O
Exact Mass: 288.15
Molecular Weight: 288.390
Elemental Analysis: C, 87.46; H, 6.99; O, 5.55
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Synonym: F 050; F-050; F050
IUPAC/Chemical Name: 3-([1,1':2',1''-terphenyl]-4'-yl)propan-1-ol
InChi Key: RWGNIRFXQDNZLG-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H20O/c22-15-7-8-17-13-14-20(18-9-3-1-4-10-18)21(16-17)19-11-5-2-6-12-19/h1-6,9-14,16,22H,7-8,15H2
SMILES Code: OCCCc1ccc(c2ccccc2)c(c1)c3ccccc3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 288.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Hongou K, Miyamae T, Hashizume H, Oshima K, Ogawa T, Hongou T, Morikawa T, Hagiwara M. Antithrombotic effects of 3-([1:1',2':1"]-3'-terphenyl)propanol in animals. Arzneimittelforschung. 1997 Oct;47(10):1104-8. PMID: 9368702.