F-1459 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H575259

CAS#: 63207-78-3

Description: F-1459 HCl is an antitussive and respiratory stimulant.


Chemical Structure

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F-1459 HCl
CAS# 63207-78-3

Theoretical Analysis

Hodoodo Cat#: H575259
Name: F-1459 HCl
CAS#: 63207-78-3
Chemical Formula: C20H25ClN2O
Exact Mass: 344.17
Molecular Weight: 344.880
Elemental Analysis: C, 69.65; H, 7.31; Cl, 10.28; N, 8.12; O, 4.64

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: F 1459 HCl; F1459 HCl; F-1459 HCl; F 1459 hydrochloride; F1459 hydrochloride; F-1459 hydrochloride

IUPAC/Chemical Name: Benzeneacetamide, alpha-phenyl-N-(2-(1-pyrrolidinyl)ethyl)-, monohydrochloride

InChi Key: DURRPOQFSGOCHC-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24N2O.ClH/c23-20(21-13-16-22-14-7-8-15-22)19(17-9-3-1-4-10-17)18-11-5-2-6-12-18;/h1-6,9-12,19H,7-8,13-16H2,(H,21,23);1H

SMILES Code: Cl.O=C(NCCN1CCCC1)C(c2ccccc2)c3ccccc3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 344.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Tarayre JP, Vilain P, Lauressergues H, Cauquil J, Bru M, Caillol V, Pouget G, Jougla AM, Go M. Pharmacological study of the antitussive and respiratory-analeptic properties of N-(2'-ethylpyrrolidino)diphenylacetamide hydrochloride (F 1459). Arzneimittelforschung. 1983;33(7):931-5. PMID: 6684929.