WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H575259
CAS#: 63207-78-3
Description: F-1459 HCl is an antitussive and respiratory stimulant.
Hodoodo Cat#: H575259
Name: F-1459 HCl
CAS#: 63207-78-3
Chemical Formula: C20H25ClN2O
Exact Mass: 344.17
Molecular Weight: 344.880
Elemental Analysis: C, 69.65; H, 7.31; Cl, 10.28; N, 8.12; O, 4.64
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Synonym: F 1459 HCl; F1459 HCl; F-1459 HCl; F 1459 hydrochloride; F1459 hydrochloride; F-1459 hydrochloride
IUPAC/Chemical Name: Benzeneacetamide, alpha-phenyl-N-(2-(1-pyrrolidinyl)ethyl)-, monohydrochloride
InChi Key: DURRPOQFSGOCHC-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H24N2O.ClH/c23-20(21-13-16-22-14-7-8-15-22)19(17-9-3-1-4-10-17)18-11-5-2-6-12-18;/h1-6,9-12,19H,7-8,13-16H2,(H,21,23);1H
SMILES Code: Cl.O=C(NCCN1CCCC1)C(c2ccccc2)c3ccccc3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 344.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Tarayre JP, Vilain P, Lauressergues H, Cauquil J, Bru M, Caillol V, Pouget G, Jougla AM, Go M. Pharmacological study of the antitussive and respiratory-analeptic properties of N-(2'-ethylpyrrolidino)diphenylacetamide hydrochloride (F 1459). Arzneimittelforschung. 1983;33(7):931-5. PMID: 6684929.