WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H412696
CAS#: 77133-35-8
Description: QNN33358 is an alkylacylglycerol acts as a protein kinase C (PKC) inhibitor and diacylglycerol (DAG) antagonist.
Hodoodo Cat#: H412696
Name: QNN33358
CAS#: 77133-35-8
Chemical Formula: C21H42O4
Exact Mass: 358.31
Molecular Weight: 358.560
Elemental Analysis: C, 70.34; H, 11.81; O, 17.85
Synonym: C16-02:0 DG; 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG); QNN33358; QNN 33358; QNN-33358
IUPAC/Chemical Name: (S)-1-(hexadecyloxy)-3-hydroxypropan-2-yl acetate
InChi Key: QTEHGUUSIIWOOW-NRFANRHFSA-N
InChi Code: InChI=1S/C21H42O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24-19-21(18-22)25-20(2)23/h21-22H,3-19H2,1-2H3/t21-/m0/s1
SMILES Code: OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 358.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Abe A, Hiraoka M, Shayman JA. The acylation of lipophilic alcohols by lysosomal phospholipase A2. J Lipid Res. 2007 Oct;48(10):2255-63. doi: 10.1194/jlr.M700277-JLR200. Epub 2007 Jul 12. PMID: 17626977.