1-C16 Ether MG
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Hodoodo CAT#: H412697

CAS#: 506-03-6

Description: 1-C16 Ether MG is a neutral lipid and is used to promote plasmalogen biosynthesis in lymphoblasts.

Chemical Structure

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1-C16 Ether MG
CAS# 506-03-6
Instruction

Theoretical Analysis

Hodoodo Cat#: H412697
Name: 1-C16 Ether MG
CAS#: 506-03-6
Chemical Formula: C19H40O3
Exact Mass: 316.30
Molecular Weight: 316.530
Elemental Analysis: C, 72.10; H, 12.74; O, 15.16

Price and Availability

Size Price Availability Quantity
250mg USD 450 2 Weeks
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Synonym: 1-C16 Ether MG; 1-O-hexadecyl-sn-glycerol (HG)

IUPAC/Chemical Name: (S)-3-(hexadecyloxy)propane-1,2-diol

InChi Key: OOWQBDFWEXAXPB-IBGZPJMESA-N

InChi Code: InChI=1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3/t19-/m0/s1

SMILES Code: [H][C@@](CO)(O)COCCCCCCCCCCCCCCCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 316.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Bozelli JC Jr, Lu D, Atilla-Gokcumen GE, Epand RM. Promotion of plasmalogen biosynthesis reverse lipid changes in a Barth Syndrome cell model. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jun;1865(6):158677. doi: 10.1016/j.bbalip.2020.158677. Epub 2020 Feb 29. PMID: 32126285.

PubMed ID: 32126285

2. Phuyal, S., T. Skotland, N.P. Hessvik, H. Simolin, A. Overbye, A. Brech, R.G. Parton, K. Ekroos, K. Sandvig, and A. Llorente. (2014). The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells. J Biol Chem [PubMed]

PubMed ID: 25519911

3. Abe, A., Hiraoka, M., Shayman, J.A. (2007) The acylation of lipophilic alcohols by lysosomal phospholipase A2. J Lipid Res 48:2255-63. [PubMed]

PubMed ID: 17626977