11-cis Retinol
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Hodoodo CAT#: H464107

CAS#: 22737-96-8

Description: 11-cis Retinol is an isomer of vitamin A. It is formed from vitamin A, via a trans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle. 11-cis Retinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells. It promotes pigment formation in cone, but not rod, photoreceptors.


Chemical Structure

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11-cis Retinol
CAS# 22737-96-8

Theoretical Analysis

Hodoodo Cat#: H464107
Name: 11-cis Retinol
CAS#: 22737-96-8
Chemical Formula: C20H30O
Exact Mass: 286.2297
Molecular Weight: 286.459
Elemental Analysis: C, 83.86; H, 10.56; O, 5.59

Price and Availability

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1.0mg USD 430.0 2 Weeks
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Synonym: 11-cis Retinol; 11 cis-Retinol; 11 cis Retinol; 11-cis-Retinol;

IUPAC/Chemical Name: (2E,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

InChi Key: FPIPGXGPPPQFEQ-IOUUIBBYSA-N

InChi Code: InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6-,12-11+,16-8+,17-13+

SMILES Code: OC/C=C(/C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Instruction:

Preparing Stock Solutions

The following data is based on the product molecular weight 286.459 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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