WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H464361
CAS#: 159934-11-9
Description: Palmarumycin C3 is a spirobisnaphthalene fungal metabolite that has been found in C. palmarum and has diverse biological activities. It is active against the bacteria A. tumefaciens, B. subtilis, P. lachrymans, R. solanacearum, S. haemolyticus, and X. vesicatoria (MICs = 6.25, 6.25, 12.5, 12.5, 6.25, and 6.25 µg/ml, respectively). Palmarumycin C3 is also active against the fungi M. microspora and E. repens, as well as the plant pathogenic fungi F. oxysporum and U. violacea, in agar diffusion assays when used at a concentration of 0.5 mg/disc. It scavenges DPPH radicals in cell-free assays and has antioxidant activity in a β-carotene-linoleic acid bleaching assay (IC50s = 37.57 and 7.41 µg/ml, respectively).
Hodoodo Cat#: H464361
Name: Palmarumycin C3
CAS#: 159934-11-9
Chemical Formula: C20H12O6
Exact Mass: 348.06
Molecular Weight: 348.310
Elemental Analysis: C, 68.97; H, 3.47; O, 27.56
Synonym: Palmarumycin C3; Palmarumycin-C3;
IUPAC/Chemical Name: (1a'R,7a'S)-3',6'-dihydroxy-1a',7a'-dihydro-7'H-spiro[naphtho[1,8-de][1,3]dioxine-2,2'-naphtho[2,3-b]oxiren]-7'-one
InChi Key: BDXBHYOFNNANPN-RTBURBONSA-N
InChi Code: InChI=1S/C20H12O6/c21-10-7-8-11(22)16-15(10)17(23)18-19(24-18)20(16)25-12-5-1-3-9-4-2-6-13(26-20)14(9)12/h1-8,18-19,21-22H/t18-,19-/m1/s1
SMILES Code: OC1=C2C3([C@]4([C@]([H])(O4)C(C2=C(O)C=C1)=O)[H])OC5=CC=CC6=C5C(O3)=CC=C6
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 348.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
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| In vivo protocol: |
1: Mou Y, Meng J, Fu X, Wang X, Tian J, Wang M, Peng Y, Zhou L. Antimicrobial and antioxidant activities and effect of 1-hexadecene addition on palmarumycin C2 and C3 yields in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Molecules. 2013 Dec 13;18(12):15587-99. doi: 10.3390/molecules181215587. PMID: 24352015; PMCID: PMC6270283.
