Valacyclovir maleate
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Hodoodo CAT#: H333062

CAS#: 950189-66-9 (maleate)

Description: Valacyclovir, also known as valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, being converted in vivo to aciclovir. Valaciclovir has been available as a generic drug in the U.S. since November 25, 2009. Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10–20%). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism. Aciclovir is selectively converted into a monophosphate form by viral thymidine kinase, which is far more effective (3000 times) in phosphorylation of aciclovir than cellular thymidine kinase.


Chemical Structure

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Valacyclovir maleate
CAS# 950189-66-9 (maleate)

Theoretical Analysis

Hodoodo Cat#: H333062
Name: Valacyclovir maleate
CAS#: 950189-66-9 (maleate)
Chemical Formula: C17H24N6O8
Exact Mass: 0.00
Molecular Weight: 440.413
Elemental Analysis: C, 46.36; H, 5.49; N, 19.08; O, 29.06

Price and Availability

Size Price Availability Quantity
200mg USD 250 2 Weeks
500mg USD 450 2 Weeks
1g USD 650 2 Weeks
2g USD 1150 2 Weeks
5g USD 1950 2 Weeks
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Related CAS #: 124832-26-4 (free base)   124832-27-5 (HCl)   950189-66-9 (maleate)    

Synonym: 256U87; BW 256; BW-256; BW256; BW-256U87; Valacyclovir; valacyclovir. Val-ACV; Valtrex; Zelitrex; Valacyclovir maleate;

IUPAC/Chemical Name: 2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl L-valinate maleate

InChi Key: LGBHMEGEVRYKJB-KZDSSNOQSA-N

InChi Code: InChI=1S/C13H20N6O4.C4H4O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;5-3(6)1-2-4(7)8/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m0./s1

SMILES Code: O=C(O)/C=C\C(O)=O.N[C@@H](C(C)C)C(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 440.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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