WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H556048
CAS#: 1220890-25-4
Description: C12-200 is potent branched-tail lipid. C12-200 is useful for the development of lipidoid nanoparticles for siRNA, mRNA, and vaccine Delivery. C12-200 formulation can increase the potency of erythropoietin-mRNA-loaded C12-200 lipid nanoparticles 7-fold relative to formulations previously used for siRNA delivery.
Hodoodo Cat#: H556048
Name: C12-200
CAS#: 1220890-25-4
Chemical Formula: C70H145N5O5
Exact Mass: 1,136.12
Molecular Weight: 1,136.960
Elemental Analysis: C, 73.95; H, 12.86; N, 6.16; O, 7.04
Synonym: C12-200; C 12-200; C-12-200; C12 200; C12200; C 12200; C-12200; Tech G 1;
IUPAC/Chemical Name: 1,1-((2-(4-(2-((2-(bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl) amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol)
InChi Key: URQSMTPJROAUPK-UHFFFAOYSA-N
InChi Code: InChI=1S/C70H145N5O5/c1-6-11-16-21-26-31-36-41-46-65(76)61-74(62-66(77)47-42-37-32-27-22-17-12-7-2)53-51-69(70(80)50-45-40-35-30-25-20-15-10-5)71-52-54-72-55-57-73(58-56-72)59-60-75(63-67(78)48-43-38-33-28-23-18-13-8-3)64-68(79)49-44-39-34-29-24-19-14-9-4/h65-71,76-80H,6-64H2,1-5H3
SMILES Code: CCCCCCCCCCC(O)C(NCCN1CCN(CCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CC1)CCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC
Appearance: Liquid
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 1,136.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |