WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H578237
CAS#: 955112-72-8 (tosylate)
Description: F-15599 tosylate is a selective 5-HT(1A) agonist.
Hodoodo Cat#: H578237
Name: F-15599 tosylate
CAS#: 955112-72-8 (tosylate)
Chemical Formula: C26H29ClF2N4O4S
Exact Mass: 566.16
Molecular Weight: 567.050
Elemental Analysis: C, 55.07; H, 5.16; Cl, 6.25; F, 6.70; N, 9.88; O, 11.29; S, 5.65
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Related CAS #: 635323-95-4 (free base) 955112-72-8 (tosylate) 635323-96-5 (fumarate)
Synonym: F-15599 tosylate; F 15599 tosylate; F15599 tosylate; NLX-101 tosylate; NLX 101 tosylate; NLX101 tosylate
IUPAC/Chemical Name: Methanone, (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methyl-2-pyrimidinyl)methyl)amino)methyl)-1-piperidinyl)-, 4-methylbenzenesulfonate (1:1)
InChi Key: MIRDQKPVJAWCBX-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H21ClF2N4O.C7H8O3S/c1-13-9-24-17(25-10-13)11-23-12-19(22)4-6-26(7-5-19)18(27)14-2-3-16(21)15(20)8-14;1-6-2-4-7(5-3-6)11(8,9)10/h2-3,8-10,23H,4-7,11-12H2,1H3;2-5H,1H3,(H,8,9,10)
SMILES Code: Cc1ccc(cc1)S(=O)(=O)O.Cc2cnc(CNCC3(F)CCN(CC3)C(=O)c4ccc(F)c(Cl)c4)nc2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 567.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Głuch-Lutwin M, Sałaciak K, Gawalska A, Jamrozik M, Sniecikowska J, Newman-Tancredi A, Kołaczkowski M, Pytka K. The selective 5-HT1A receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress. Psychopharmacology (Berl). 2021 Aug;238(8):2249-2260. doi: 10.1007/s00213-021-05849-0. Epub 2021 May 10. PMID: 33973045; PMCID: PMC8292235.