WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H406210
CAS#: 71897-07-9
Description: AG1295 is a PDGF receptor specific inhibitor. AG1295 exerts a marked inhibitory effect on the activation, migration, and proliferation of porcine and human smooth muscle cells SMCs in vitro and an approximately 50% inhibitory effect on neointimal formation after balloon injury in porcine femoral arteries when delivered via biodegradable nanoparticles. Further studies appear to be warranted to evaluate the applicability of this novel approach to the interventional setting.
Hodoodo Cat#: H406210
Name: AG1295
CAS#: 71897-07-9
Chemical Formula: C16H14N2
Exact Mass: 234.12
Molecular Weight: 234.300
Elemental Analysis: C, 82.02; H, 6.02; N, 11.96
Synonym: AG1295; AG-1295; AG 1295; NSC 380341; Tyrphostin AG 1295.
IUPAC/Chemical Name: 6,7-dimethyl-2-phenylquinoxaline
InChi Key: FQNCLVJEQCJWSU-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H14N2/c1-11-8-14-15(9-12(11)2)18-16(10-17-14)13-6-4-3-5-7-13/h3-10H,1-2H3
SMILES Code: CC1=C(C)C=C2N=CC(C3=CC=CC=C3)=NC2=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 234.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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