WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H406412
CAS#: 842122-14-9
Description: NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity.
Hodoodo Cat#: H406412
Name: NU-7200
CAS#: 842122-14-9
Chemical Formula: C17H17NO4
Exact Mass: 299.12
Molecular Weight: 299.321
Elemental Analysis: C, 68.21; H, 5.72; N, 4.68; O, 21.38
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Synonym: NU-7200; NU 7200; NU7200.
IUPAC/Chemical Name: 2-((2-(2-hydroxyethoxy)ethyl)amino)-4H-benzo[h]chromen-4-one
InChi Key: UQJNMNYCRLPGSK-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H17NO4/c19-8-10-21-9-7-18-16-11-15(20)14-6-5-12-3-1-2-4-13(12)17(14)22-16/h1-6,11,18-19H,7-10H2
SMILES Code: O=C1C=C(NCCOCCO)OC2=C1C=CC3=CC=CC=C32
Appearance: solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 299.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Nutley BP, Smith NF, Hayes A, Kelland LR, Brunton L, Golding BT, Smith GC, Martin NM, Workman P, Raynaud FI. Preclinical pharmacokinetics and metabolism of a novel prototype DNA-PK inhibitor NU7026. Br. J. Cancer (2005).