Paclitaxel-Succinic acid
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Hodoodo CAT#: H620101

CAS#: 117527-50-1 (Paclitaxel-Succinic acid)

Description: Paclitaxel-Succinic acid, also known as Paclitaxel Succinate or Paclitaxel-hemisuccinic acid, is a paclitaxel derivative with a succinic acid linker. The carboxy group of Paclitaxel-Succinic acid, after activiating, can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. Note: DCN10809, also known as Paclitaxel succinate NHS ester (Cat#408092) is also in stock.


Chemical Structure

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Paclitaxel-Succinic acid
CAS# 117527-50-1 (Paclitaxel-Succinic acid)

Theoretical Analysis

Hodoodo Cat#: H620101
Name: Paclitaxel-Succinic acid
CAS#: 117527-50-1 (Paclitaxel-Succinic acid)
Chemical Formula: C51H55NO17
Exact Mass: 953.35
Molecular Weight: 953.990
Elemental Analysis: C, 64.21; H, 5.81; N, 1.47; O, 28.51

Price and Availability

Size Price Availability Quantity
5mg USD 90 Ready to ship
10mg USD 150 Ready to ship
25mg USD 250 Ready to ship
50mg USD 450 Ready to ship
100mg USD 750 Ready to ship
200mg USD 1350 Ready to ship
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Related CAS #: 186040-50-6 (ceribate)   33069-62-4 (free base)   263351-82-2 (Poliglumex)   Paclitaxel-SMCC   117527-50-1 (Paclitaxel-Succinic acid)   Paclitaxel-MVCP  

Synonym: Paclitaxel-Succinic acid; Paclitaxel Succinate; Paclitaxel-hemisuccinic acid; Paclitaxel-SA;

IUPAC/Chemical Name: 4-(((1S,2R)-1-benzamido-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-diacetoxy-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-3-oxo-1-phenylpropan-2-yl)oxy)-4-oxobutanoic acid

InChi Key: RBNOJYDPFALIQZ-LAVNIZMLSA-N

InChi Code: InChI=1S/C51H55NO17/c1-27-33(66-47(62)41(67-37(58)23-22-36(56)57)39(30-16-10-7-11-17-30)52-45(60)31-18-12-8-13-19-31)25-51(63)44(68-46(61)32-20-14-9-15-21-32)42-49(6,34(55)24-35-50(42,26-64-35)69-29(3)54)43(59)40(65-28(2)53)38(27)48(51,4)5/h7-21,33-35,39-42,44,55,63H,22-26H2,1-6H3,(H,52,60)(H,56,57)/t33-,34-,35+,39-,40+,41+,42-,44-,49+,50-,51+/m0/s1

SMILES Code: [H][C@@]1([C@@H]([C@@](C2(C)C)(C[C@@H](C(C)=C2[C@H](C([C@]([C@H](C[C@]34[H])O)1C)=O)OC(C)=O)OC([C@@H]([C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)OC(CCC(O)=O)=O)=O)O)OC(C7=CC=CC=C7)=O)[C@@]3(CO4)OC(C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related product: CAT#408092 Paclitaxel succinate NHS ester; DCN10809; DCN-10809; DCN 10809; Paclitaxel-Succinic acid NHS ester https://www.medkoo.com/products/37914

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 953.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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