Pivmecillinam Hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H318550

CAS#: 32887-03-9

Description: Pivmecillinam hydrochloride is active against gram-negative organisms and used as for amdinocillin. Pivmecillinam is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic.


Chemical Structure

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Pivmecillinam Hydrochloride
CAS# 32887-03-9

Theoretical Analysis

Hodoodo Cat#: H318550
Name: Pivmecillinam Hydrochloride
CAS#: 32887-03-9
Chemical Formula: C21H34ClN3O5S
Exact Mass: 0.00
Molecular Weight: 476.030
Elemental Analysis: C, 52.99; H, 7.20; Cl, 7.45; N, 8.83; O, 16.81; S, 6.74

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Pivmecillinam Hydrochloride; Melysin; Pivmecillinam (hydrochloride); UNII-48FX7N21H2; Pivmecilinamo clorhidrato [Spanish]; Pivmecillinam Hydrochloride; Pivoxil, Amdinocillin; Selexid;

IUPAC/Chemical Name: 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrochloride

InChi Key: UHPXMYLONAGUPC-RSRKELGKSA-N

InChi Code: InChI=1S/C21H33N3O5S.ClH/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23;/h12,14-15,17H,6-11,13H2,1-5H3;1H/b22-12+;

SMILES Code: CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C)C.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 476.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Anderson JD, Adams MA. Urinary excretion of mecillinam by volunteers receiving
film-coated tablets of pivmecillinam hydrochloride. Chemotherapy. 1979;25(1):1-4.
PubMed PMID: 217572.


2: Henrion R, Vige P. [Clinical study of pivmecillinam hydrochloride in lower
urinary tract infections in pregnant women. Apropos of 44 cases]. Rev Fr Gynecol
Obstet. 1987 Dec;82(12):761-4. French. PubMed PMID: 3324273.


3: Kjer JJ, Ottesen B. Pharmacokinetics of pivmecillinam hydrochloride in
pregnant and non-pregnant women. Acta Pharmacol Toxicol (Copenh). 1986
Nov;59(5):430-1. PubMed PMID: 3811971.


4: Hagel RB, Waysek EH. Stability-indicating assay for pivmecillinam
hydrochloride and pivmecillinam hydrochloride capsules. J Chromatogr. 1979 Oct
19;178(1):97-14. PubMed PMID: 231046.