GSK137647A
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H526617

CAS#: 349085-82-1

Description: GSK137647A is an agonist of the free fatty acid receptor 4 (FFA4/GPR120) with pEC50s = 6.3, 6.2, and 6.1 at human, mouse, and rat receptors, respectively. GSK137647A is selective for GPR120 over a panel of 61 other targets, including other FFARs.


Chemical Structure

img
GSK137647A
CAS# 349085-82-1

Theoretical Analysis

Hodoodo Cat#: H526617
Name: GSK137647A
CAS#: 349085-82-1
Chemical Formula: C16H19NO3S
Exact Mass: 305.11
Molecular Weight: 305.392
Elemental Analysis: C, 62.93; H, 6.27; N, 4.59; O, 15.72; S, 10.50

Price and Availability

Size Price Availability Quantity
100mg USD 450 2 Weeks
200mg USD 750 2 Weeks
500mg USD 1250 2 Weeks
1g USD 2050 2 Weeks
Bulk inquiry

Synonym: GSK137647A; GSK-137647A; GSK 137647A; GSK137647; GSK-137647; GSK 137647.

IUPAC/Chemical Name: 4-methoxy-N-(2,4,6-trimethylphenyl)-benzenesulfonamide

InChi Key: FQUAFMNPXPXOJE-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3

SMILES Code: O=S(C1=CC=C(OC)C=C1)(NC2=C(C)C=C(C)C=C2C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 305.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S,
Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele
T, Vulimiri P, Way JM, Ross S. Identification of diarylsulfonamides as agonists
of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg Med Chem Lett. 2014 Jul
15;24(14):3100-3. doi: 10.1016/j.bmcl.2014.05.012. Epub 2014 May 16. PubMed PMID:
24881566.