CK 17

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H524742

CAS#: 86727-00-6

Description: CK 17 is a interleukin-1 antagonist. It is a IL-1 blocker that suppresses fibroblast proliferation in a concentration-dependent manner.

Chemical Structure

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CK 17
CAS# 86727-00-6
Instruction

Theoretical Analysis

Hodoodo Cat#: H524742
Name: CK 17
CAS#: 86727-00-6
Chemical Formula: C17H15BrN2OS
Exact Mass: 374.01
Molecular Weight: 375.280
Elemental Analysis: C, 54.41; H, 4.03; Br, 21.29; N, 7.46; O, 4.26; S, 8.54

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: CK 17; CK17; CK-17.

IUPAC/Chemical Name: 5-Bromotetrahydro-5-methyl-3-phenyl-2-(phenylimino)-4H-1,3-thiazin-4-one

InChi Key: ASZBPWIGUHLPML-DOMQTXCISA-N

InChi Code: InChI=1S/C17H15BrN2OS/c1-17(18)12-22-16(19-13-8-4-2-5-9-13)20(15(17)21)14-10-6-3-7-11-14/h2-11H,12H2,1H3/b19-16-/t17-/m0/s1

SMILES Code: S1\C(N(C([C@@](C1)(C)Br)=O)c1ccccc1)=N/c1ccccc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 375.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Chen Z, Liu SX, Chiou GC. Inhibitory effects of interleukin-1 blockers on corneal fibroblast proliferation. J Ocul Pharmacol Ther. 1996 Summer;12(2):169-82. PubMed PMID: 8773933.