MK 0767

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H525638

CAS#: 934017-32-0

Description: MK 0767 is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, has been studied as a potential treatment of type 2 diabetes and dyslipidemia.

Chemical Structure

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MK 0767
CAS# 934017-32-0
Instruction

Theoretical Analysis

Hodoodo Cat#: H525638
Name: MK 0767
CAS#: 934017-32-0
Chemical Formula: C19H15F3N2O4S
Exact Mass: 424.07
Molecular Weight: 424.394
Elemental Analysis: C, 53.77; H, 3.56; F, 13.43; N, 6.60; O, 15.08; S, 7.55

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: MK 0767; MK-0767; MK0767

IUPAC/Chemical Name: 5-(2,4-dioxothiazolidin-5-yl)-2-methoxy-N-(4-(trifluoromethyl)benzyl)benzamide

InChi Key: PUJCSYJMQMUYPS-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H15F3N2O4S/c1-28-14-7-4-11(15-17(26)24-18(27)29-15)8-13(14)16(25)23-9-10-2-5-12(6-3-10)19(20,21)22/h2-8,15H,9H2,1H3,(H,23,25)(H,24,26,27)

SMILES Code: O=C(NCC1=CC=C(C(F)(F)F)C=C1)C2=CC(C(SC(N3)=O)C3=O)=CC=C2OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 424.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Rippley RK, Yan KX, Matthews ND, Greenberg HE, Herman GA, Wagner JA. Human
pharmacokinetics and interconversion of enantiomers of MK-0767, a dual
PPARalpha/gamma agonist. J Clin Pharmacol. 2007 Mar;47(3):323-33. PubMed PMID:
17322144.