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Featured Products
PF 1022A
CAT#: H585005
CAS#: 133413-70-4
PF 1022A is an anthelmintic depsipeptide isolated from Mycelia Sterilia.
PF-02413873
CAT#: H525925
CAS#: 936345-35-6
PF-02413873 is a nonsteroidal progesterone receptor antagonist. It is used for the treatment of gynecological conditions such as endometriosis.
PF-03246799 hydrochloride
CAT#: H471096
CAS#: 1065114-52-4
PF-03246799 hydrochloride is a potent serotonin 5-HT2C receptor agonist.
PF-03654746 Tosylate
CAT#: H471153
CAS#: 1039399-17-1 (tosylate)
PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist. It is undergoing clinical trials for the treatment of ADHD, Tourette …
PF-03716556
CAT#: H526742
CAS#: 928774-43-0
PF-03716556 is a potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. PF-03716556 demonstrated 3-fold gre…
PF-03758309
CAT#: H205581
CAS#: 898044-15-0 (free base)
PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also an orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) w…
PF-03814735
CAT#: H205987
CAS#: 942487-16-3
PF-03814735 is an orally bioavailable, ATP-competitive, reversible small-molecule Aurora kinase inhibitor with potential antineoplastic activity. Auro…
PF-03882845
CAT#: H525939
CAS#: 1023650-66-9
PF-03882845 is a highly potent (IC50=6.3‐13.4nM,10% fetal bovine serum & IC50= 0.504–1.11 nM, absence of serum) selective orally bioavailable mineralo…
PF-04217903
CAT#: H202221
CAS#: 956905-27-4 (free base)
PF-04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (…
PF-04217903 mesylate
CAT#: H206862
CAS#: 956906-93-7 (mesylate)
PF-04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (…
PF-04279405
CAT#: H531383
CAS#: 955881-01-3
PF-04279405 is a potent and selective glucokinase activator.
PF-04363467 HCl
CAT#: H563738
CAS#: 2040055-81-8
PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist.
PF-04445597
CAT#: H531382
CAS#: 949099-81-4
PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP).
PF-04449613
CAT#: H462312
CAS#: 1236858-52-8
PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor. Subcutaneous administration of PF-04449613 (10 mg/kg) increases the rate of dendritic spine f…
PF-04457845
CAT#: H522480
CAS#: 1020315-31-4
PF-04457845 is a potent and exquisitely selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50 of 7.2nM, and both analgesic…
PF-04479745 free base
CAT#: H525217
CAS#: 1065110-43-1 (free base)
PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a precli…
PF-04531083
CAT#: H531381
CAS#: 1079400-07-9
PF-04531083 is an orally available, potent and selective sodium channel Nav1.8 blocker. PF-04531083 was designated as a potential treatment of pain.
PF-04620110
CAT#: H526744
CAS#: 1109276-89-2
PF-04620110 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that inhibits triacylglycerol synthe…
PF-04628935
CAT#: H530929
CAS#: 1383719-97-8
PF-04628935 is is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 n…
PF-04671536
CAT#: H531377
CAS#: 1305116-69-1
PF-04671536 is a highly potent and selective inhibitor of phosphodiesterase 8B (PDE8B) phosphodiesterase 8A (PDE8A). In primary human pancreatic islet…
PF-04691502
CAT#: H202226
CAS#: 1013101-36-4
PF-04691502 is a PI3K/mTOR kinase inhibitor , is also an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (m…
PF-04701475
CAT#: H531375
CAS#: 1488407-52-8
PF-04701475is a potent and selective α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) positive allosteric potentiator.
PF-04745637
CAT#: H526857
CAS#: 1917294-46-2
PF-04745637 is a TRPV1 antagonist. PF-04745637 is acts as a potent and selective antagonist for the TRPA1 receptor, with an IC50 of 17nM, vs ~3μM at …
PF-04753299
CAT#: H531372
CAS#: 1289620-49-0
PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine …
PF-04802367
CAT#: H471098
CAS#: 1962178-27-3
PF-04802367 is a highly selective GSK-3 inhibitor
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