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Newest Products
ML-141
CAT#: H530539
CAS#: 71203-35-5
ML-141, also known as CID2950007, is a Cdc42 inhibitor (EC50 = 2.1 µM).
LSN2463359
CAT#: H532121
CAS#: 1401031-52-4
LSN2463359 is a novel positive allosteric modulators of the mGlu₅ receptor.
LP-471756
CAT#: H532118
CAS#: 413605-11-5
LP-471756 is antagonist of GPR139.
OTS514 HCl
CAT#: H558256
CAS#: 2319647-76-0 (HCl)
OTS514 is a potent TOPK (T-LAK cell-originated protein kinase) inhibitor. OTS514 exhibits growth suppressive effect on small cell lung cancer. TS514 …
ML-7 HCl
CAT#: H530537
CAS#: 110448-33-4
ML-7 is a MLCK inhibitor. ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM. ML-7 amplifies the quinocetone-induc…
ITH-12575
CAT#: H530536
CAS#: 1802013-08-6
ITH-12575 is a Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor. ITH12575 reduced Ca(2+) influx through CALHM1 at low micromolar concentrations.
ML-339
CAT#: H407416
CAS#: 2579689-83-9 (free base)
ML-339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM).
PF-05231023
CAT#: H530533
CAS#: 1037589-69-7
PF-05231023 is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and improves lipid profile in non-human primates and in type 2 diabetic…
PF-06291874
CAT#: H530531
CAS#: 1393124-08-7
PF-06291874 is a glucagon receptor antagonist that is potentially useful for patients with type 2 diabetes mellitus. PF-06291874 was well tolerated, h…
Grassofermata
CAT#: H407413
CAS#: 419547-11-8
Grassofermata, also known as NAV-2729, is a selective ARF6 inhibitor (IC50 = 1.0 μM). Blocking ARF6 with a small-molecule inhibitor reduces uveal me…
AZD-5099
CAT#: H528415
CAS#: 907543-25-3
AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.
TMC-310911
CAT#: H529115
CAS#: 1000287-05-7
TMC-310911, also known as ASC-09, is an HIV protease inhibitor potentially for the treatment of HIV infection.
Salermide
CAT#: H407409
CAS#: 1105698-15-4
Salermide is a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Salermide was well tolerated by mice at concentrations up to 100 m…
L-371,257
CAT#: H532059
CAS#: 162042-44-6
L-371,257 is a potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays > 800-fold selectivity over human arginine v…
Abacavir hydroxyacetate
CAT#: H529107
CAS#: 1446418-48-9 (hydroxyacetate)
Prurisol, also known as abacavir hydroxyacetate and KM-133, is potentially for the treatment of plaque psoriasis
L-168049
CAT#: H532054
CAS#: 191034-25-0
L-168,049 is a non-peptidyl human glucagon receptor antagonist.
BAY-598 R-isomer
CAT#: H407403
CAS#: 1906920-28-2 (BAY598 R-isomer)
BAY-598 R-isomer is the R-isomer of BAY589. BAY-598 R-isomer may be used as a reference compound. BAY-598 is a potent, peptide-competitive chemical p…
Obefazimod
CAT#: H529212
CAS#: 1258453-75-6
Obefazimod, also known as SPL-464 and ABX-464, is an inhibitor of the HIV replication potentially for the treatment of HIV infection.
H2L5186303
CAT#: H531950
CAS#: 139262-76-3
H2L5186303 is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 values are 8.9, 1230 and 27354 nM).
GSK5182
CAT#: H531877
CAS#: 877387-37-6 (free base)
GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
GSK4112
CAT#: H531875
CAS#: 1216744-19-2
GSK4112 is a selective Rev-Erbα agonist (EC50 = 250 nM). GSK4112 enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erbα and …
Exatecan mesylate
CAT#: H206786
CAS#: 169869-90-3 (mesylate)
Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits t…
AAI-101
CAT#: H527715
CAS#: 1001404-83-6 (free form)
Enmetazobactam, also known as AAI-101, is a novel β-lactam/β-lactamase inhibitor. AAI101 is similar in structure to tazobactam, with one important d…
CXA-10
CAT#: H527714
CAS#: 875685-46-4
CXA-10, also known as 10-Nitrooleic acid, is an endogenous nitro-fatty acid (NFA) modulator of Nrf2 and NF-κB potentially for the treatment of acute k…
GLPG0974
CAT#: H531847
CAS#: 1391076-61-1
GLPG0974 is a potent and selective FFA2 antagonist.
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