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16
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19
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10
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20
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17
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2
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Akt Products
or product name starting with:
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H205525
LY2780301
LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein ki…
H406418
LB42708
featured
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase in…
H205776
KU-0063794
featured
KU-0063794 is a potent and selective mTOT inhibitor, which inhibits both mTORC1 and mTORC2 with an I…
H203060
KRX-0601
featured
KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activ…
H205482
GSK-2256098
featured
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential ant…
H205739
GSK1059615
featured
GSK1059615 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. P…
H205472
GGTI-2418
featured
GGTI-2418, also known as PTX100, is a synthetic peptidomimetic inhibitor of geranylgeranyltransferas…
H205798
GFB-204
GFB-204 is a calixarene derivative that is a potent and selective inhibitor of VEGFR and PDGFR tyros…
H201310
Etalocib
new
featured
Etalocib, also known as LY293111 and VML295, is a novel diaryl ether carboxylic acid derivative, is …
H201300
Spisulosine
Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynom…
H201266
Entinostat
featured
Entinostat, also known as MS-275 or SNDX-275, is a potent HDAC inhibitor with potential antineoplas…
H205961
DS-3078a
DS-3078a is an orally bioavailable inhibitor of raptor-mTOR protein complex (TORC1) and rictor-mTOR …
H205924
Fimepinostat
featured
CUDC-907, also known as fimepinostat, is an orally bioavailable inhibitor of both phosphoinositide 3…
H205747
CH5132799
featured
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a strong inhibi…
H205829
CC-115
new
featured
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamyci…
H200521
BMS-536924
featured
BMS-536924 is a potent small molecule inhibitor of IGF-IR, which shows antitumor activity in multipl…
H204676
BIIB028
BIIB028 is a small-molecule inhibitor of heat shock protein (Hsp) 90 with potential antineoplastic a…
H200505
BIIB021
featured
BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of he…
H200492
BGT226 free base
featured
BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. P…
H200491
Dactolisib
featured
Dactolisib, also known as BEZ235, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inh…
H206151
BAY1125976 HCl
BAY1125976 is an orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein k…
H205923
BAY1082439
featured
BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha…
H200312
AZD-8055
featured
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic a…
H200281
Miransertib free base
featured
Miransertib, also known as ARQ 092, is an oral activie, potent and selective AKT inhibitor with IC50…
H200272
OSU-03012
featured
OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown…
H200121
AG-490
new
featured
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal tr…
H202042
ADW742
featured
NVP-ADW742, also known as ADW-742 or GSK 552602A, is a novel small weight molecular inhibitor of IG…
H202870
Temsirolimus
featured
Temsirolimus is an ester analog of rapamycin. Temsirolimus binds to and inhibits the mammalian targe…
H201890
Miltefosine
featured
Miltefosine is an orally- and topically-active alkyl-phosphocholine compound with potential antineop…
H100490A
Lapatinib (free base)
featured
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatini…
H406127
TAE226
featured
TAE226 is a novel and potent ATP competitive inhibitor of FAK and IGF-IR with potential anticancer a…
H205481
Uprosertib
new
featured
Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/t…
H204930
Tucidinostat HCl
featured
Tucidinostat (also known as HBI-8000, Chidamide, and CS-055) is a benzamide type inhibitor of histon…
H205670
GSK-690693
featured
GSK690693 is a pan-AKT kinase inhibitor, is also a n aminofurazan-derived inhibitor of Akt kinases w…
H205669
Capivasertib
featured
AZD5363, also known as Capivasertib, is an orally available inhibitor of the serine/threonine protei…
H406553
UNC569
featured
UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in…
H406661
CAL-130
CAL-130 is a potent and selective PI3K gamma and delta inhibitor with potential anticancer activity.…
H406643
ISA-2011B
featured
ISA-2011B is a PIP5Kα (Phosphatidylinositol-4-phosphate 5-kinase-α) inhibitor. The overexpression of…
H406624
SC66
new
featured
SC66 is a novel and potent AKT inhibitor, which reduced cell viability in a dose- and time-dependent…
H406603
ESI-09
featured
ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intr…
H406260
AZD8186
new
featured
AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential ant…
H201458
Trametinib
featured
Trametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen-activated prot…
H207181
ONC-201
Dordaviprone, also known as ONC-201 and TIC10, is a potent, orally active, and stable small molecul…
H202228
PF-562271 Besylate
featured
PF-562271 Besylate, also known as PF-562,271 and PF-271, is an orally bioavailable small molecule an…
H202133
Palomid-529
featured
Palomid 529, also known as P529, is a novel PI3K/Akt/mTOR inhibitor. Palomid 529 (P529) inhibits the…
H201681
KU-55933
featured
KU-55933 is an ATM inhibitor, which blocks the phosphorylation of Akt induced by insulin and insulin…
H205487
HSP-990
featured
HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential ant…
H205844
GSK2636771
featured
GSK2636771 is an orally bioavailable, substituted benzimidazole inhibitor of the class I phosphoinos…
H205480
Omipalisib
featured
Omipalisib, also known as GSK2126458, is a small-molecule pyridylsulfonamide inhibitor of phosphatid…
H201072
Golvatinib
featured
Golvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyt…
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