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Newest Products
PIK-93
CAT#: H406325
CAS#: 593960-11-3
PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinase beta enzyme, and small interfering RNA-mediated down-regulatio…
PIK-90
CAT#: H406326
CAS#: 677338-12-4
PIK-90 is a potent PI3K inhibitor with potential anticancer activity.
PFI-1
CAT#: H406261
CAS#: 1403764-72-6
PFI-1 is a potent and highly selective protein interaction Inhibitor, which targets BET bromodomain. PFI-1 that efficiently blocks the interaction of …
PD089828
CAT#: H406476
CAS#: 179343-17-0
PD089828 is a potent FGFR inhibitor, which inhibits human full-length fibroblast growth factor (FGF) receptor-1 (FGFR-1), platelet-derived growth fact…
PD-173955
CAT#: H406164
CAS#: 260415-63-2
PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 ha…
NVP-BEP800
CAT#: H401562
CAS#: 847559-80-2
NVP-BEP800, also known as BEP-800, is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH(2)-terminal ATP-binding pocket of …
CAY10585
CAT#: H401535
CAS#: 934593-90-5
CAY10585, also known as LW6, was first identified and reported by a group scientists from Korea. LW8 was found to inhibits the accumulation of HIF-1al…
HS-173
CAT#: H406355
CAS#: 1276110-06-5
HS-173 is a potent PI3Kα inhibitor with potential anticancer activity. HS-173 inhibited the PI3K signaling pathway, and showed anti-proliferative effe…
GO-6976
CAT#: H406206
CAS#: 136194-77-9
GO 6976, also known as PD-406976, is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. Gö 6976 blocked neurotrophin-induced sign…
Droxinostat
CAT#: H401430
CAS#: 99873-43-5
Droxinostat, also known as NS 41080, is a selective inhibitor of HDAC3, HDAC6, and HDAC8. Droxinostat shows comparable inhibition of HDAC6 and HDAC8 (…
BGP-15 HCl
CAT#: H406369
CAS#: 66611-37-8 (HCl)
BGP-15 is a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. BG…
b-AP15
CAT#: H406452
CAS#: 1009817-63-3
b-AP15 is a novel inhibitor of proteasome deubiquitination. b-AP15 displays antitumor activity in several preclinical, solid tumor models. b-AP15 trig…
AZ-960
CAT#: H406191
CAS#: 905586-69-8
AZ960 is a novel inhibitor of Jak2 kinase. AZ960 inhibits JAK2 kinase with a K(i) of 0.00045 microm in vitro and treatment of TEL-JAK2 driven Ba/F3 ce…
FLX925 (AMG-925)
CAT#: H406521
CAS#: 1401033-86-0
FLX925, also known as AMG-925, is a potent and selective type 1 inhibitor of FLT3 that retains its cellular potency against clinically relevant secon…
AG1295
CAT#: H406210
CAS#: 71897-07-9
AG1295 is a PDGF receptor specific inhibitor. AG1295 exerts a marked inhibitory effect on the activation, migration, and proliferation of porcine and …
ABT-100
CAT#: H406416
CAS#: 450839-40-4 (free base)
ABT-100 is an orally bioavailable farnesyltransferase inhibitor. ABT-100 inhibited proliferation of cells in vitro carrying oncogenic H-Ras (EJ-1 blad…
A-966492
CAT#: H406362
CAS#: 934162-61-5
A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole …
Motolimod
CAT#: H203153
CAS#: 926927-61-9
Motolimod, also known as VTX-2337, is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activit…
VLX1570
CAT#: H206324
CAS#: 1431280-51-1
VLX1570 is an inhibitor of the 19S proteasome-specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with apoptosis-inducing and antineoplastic act…
Ulodesine
CAT#: H206081
CAS#: 548486-59-5 (free base)
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout…
TG100-115
CAT#: H202892
CAS#: 677297-51-7
TG100-115, inhibited PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively), whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μ…
Tacedinaline (CI-994)
CAT#: H205997
CAS#: 112522-64-2
Tacedinaline, also known as CI-944 and PD123654, is a n orally bioavailable substituted benzamide derivative with potential antineoplastic activity. T…
Sulfatinib
CAT#: H206205
CAS#: 1308672-74-3
Sulfatinib, also known as surufatinib, is an orally bioavailable, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, …
RX-3117
CAT#: H206092
CAS#: 865838-26-2
RX-3117, also known as TV-1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplasti…
RRx-001
CAT#: H205870
CAS#: 925206-65-1
RRx-001, also known as ABDNAZ, is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dila…
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