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Newest Products
Tenalisib
CAT#: H206093
CAS#: 1639417-53-0
Tenalisib, also known as RP6530, is a potent and selective dual PI3Kδ/γ inhibitor that inhibited growth of B-cell lymphoma cell lines with a concomita…
RO5045337
CAT#: H202421
CAS#: 939981-39-2
RO5045337, also known as RG7112, is a MDM2 antagonist with potential antineoplastic activity.
Elacestrant HCl
CAT#: H206202
CAS#: 1349723-93-8 (HCl)
Elacestrant, also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SER…
Bimiralisib free base
CAT#: H206146
CAS#: 1225037-39-7 (free base)
Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target…
Plitidepsin
CAT#: H200150
CAS#: 137219-37-5
Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activitie…
PIK-75
CAT#: H202238
CAS#: 372196-67-3 (free base)
PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 …
PI-103
CAT#: H202235
CAS#: 371935-74-9 (free base)
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, P…
PH-797804
CAT#: H206022
CAS#: 586379-66-0
PH-797804 is a potent and selectiove inhibitor of p38 mitogen-activated protein (MAP) kinase. PH-797804 reduces tumor growth of the three PDXs, which …
PFK-158
CAT#: H206166
CAS#: 1462249-75-7
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with p…
PF-04691502
CAT#: H202226
CAS#: 1013101-36-4
PF-04691502 is a PI3K/mTOR kinase inhibitor , is also an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (m…
OSI-930
CAT#: H202100
CAS#: 728033-96-3
OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits …
ONT-093
CAT#: H202055
CAS#: 216227-54-2
ONT-093, also known as OC-144-093, is an orally bioavailable P-glycoprotein pump inhibitor, for the potential reversal of multidrug resistance in pati…
AV-412 Tosylate
CAT#: H200944
CAS#: 451493-31-5 (tosylate)
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhi…
MKC-1
CAT#: H201920
CAS#: 125313-92-0
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabo…
Marimastat (BB-2516)
CAT#: H201802
CAS#: 154039-60-8
Marimastat, aslo known as BB-2516 and TA-2516, is an orally-active synthetic hydroxamate and inhibitor of matrix metalloproteinases with potential an…
LP-261
CAT#: H201761
CAS#: 915412-67-8
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer…
Incyclinide
CAT#: H201520
CAS#: 15866-90-7
Iincyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and a chemically-modified tetracycline with potential antineoplastic activity. Incycli…
Encequidar mesylate
CAT#: H401510
CAS#: 849675-87-2 (mesylate)
Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. …
HA14-1
CAT#: H201460
CAS#: 65673-63-4
HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. HA14-1 suppressed NF-ka…
GSK-461364
CAT#: H205667
CAS#: 929095-18-1
GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Pol…
GSK2879552
CAT#: H206158
CAS#: 1401966-69-5
GSK2879552 is an orally available, irreversible, inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity. Upon admin…
Cobimetinib
CAT#: H203185
CAS#: 934660-93-2 (free base)
Cobimetinib, also known as GDC-0973 and XL-518, RG 7420, is an orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase…
Falnidamol
CAT#: H205950
CAS#: 196612-93-8
Falnidamol, also known as BIBX 1382, is a pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of …
Exatecan free base
CAT#: H201340
CAS#: 171335-80-1 (free base)
Exatecan, also known as DX 8951, is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits…
Etalocib
CAT#: H201310
CAS#: 161172-51-6
Etalocib, also known as LY293111 and VML295, is a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygena…
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