Iloperidone

CAT#: H318053

CAS#: 133454-47-4

Description: Iloperidone is an atypical antipsychotic for the treatment of schizophrenia symptoms.

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Synthetic Routes

Iloperidone - Synthetic Route 1

Iloperidone route01

Synthetic reference

Process for preparing iloperidone and its salts; Dwivedi, Shriprakash Dhar; Patel, Dhimant Jasubhai; Shah, Alpesh Pravinchandra; Assignee Cadila Healthcare Limited, India; 2013; Patent Information; Jun 28, 2013; IN 2010MU03103 A

Iloperidone - Synthetic Route 2

Iloperidone route02

Synthetic reference

Duan, Pingping; Yang, Yunfang; Ben, Rong; Yan, Yiyong; Dai, Lu; Hong, Mei; Wu, Yun-Dong; Wang, Dongqi; Zhang, Xinhao; Zhao, Jing; Chemical Science; Volume 5; Issue 4; Pages 1574-1578; Journal; 2014

Iloperidone - Synthetic Route 3

Iloperidone route03

Synthetic reference

Liu, Kai-Jian; Jiang, Si; Lu, Ling-Hui; Tang, Ling-Li; Tang, Shan-Shan; Tang, Hai-Shan; Tang, Zilong; He, Wei-Min; Xu, Xinhua. Bis(methoxypropyl) ether-promoted oxidation of aromatic alcohols into aromatic carboxylic acids and aromatic ketones with O2 under metal- and base-free conditions. Green Chemistry. Volume 20. Issue 13. Pages 3038-3043. 2018.

Iloperidone - Synthetic Route 4

Iloperidone route04

Synthetic reference

Hartwig, Jan; Kirschning, Andreas. Flow Synthesis in Hot Water: Synthesis of the Atypical Antipsychotic Iloperidone. Chemistry - A European Journal. Volume 22. Issue 9. Pages 3044-3052. 2016.

Iloperidone - Synthetic Route 5

Iloperidone route05

Synthetic reference

Rao, Dodda Mohan; Reddy, Pingili Krishna; Reddy, Buthukuri Venkat. Processes for the preparation of 4'-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone and intermediates thereof. Assignee Symed Labs Limited, India. WO 2012032532. (2012).

Iloperidone - Synthetic Route 6

Iloperidone route06

Synthetic reference

Wang, Pan; Liu, Qing; Xu, Long-peng; Shang, Zhen-hua. New synthetic process of iloperidone. Zhongguo Xinyao Zazhi. Volume 22. Issue 24. Pages 2929-2932. 2013.

Iloperidone - Synthetic Route 7

Iloperidone route07

Synthetic reference

Zhou, Ruguo. Method for preparation of Iloperidone.Assignee Anhui Yuekang Kaiyue Pharmaceutical Co., Ltd., Peop. Rep. China. CN 103130785. (2013).