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PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases...
PY-60 is a novel activator of YAP, promoting expansion of epidermal keratinocytes ex vivo and in vivo, targeting...
Mibampator, also known as LY-451395, is an AMPA receptor potentiator under development for agitation/aggression in...
HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7. HBX 41108 inhibits USP7 deubiquitinating activity...
CAS#: 471843-75-1 (HCl)
Y-39983, also known as Y-33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK....
NS-11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). BK channel activation...
NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell...
NPS-1034 is a novel MET inhibitor, which inhibits the activated MET receptor and its constitutively active mutants....
CAS#: 291758-32-2 (HCl)
nor-NOHA, also known as N-Hydroxy-nor-L-Arginine, is an Arginase inhibitor. nor-NOHA induces apoptosis in...
Norbergenin, also known as Demethylbergenin, is the O-demethyl derivative of bergenin, the main component of Mallotus...
CAS#: 152946-68-4 (HCl salt)
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II...
NNC 55-0396 HCl
CAS#: 357400-13-6 (HCl)
NNC 55-0396 is a T-type calcium channel blocker. NNC 55-0396 inhibits angiogenesis via suppression of...
NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol...
NKY80 is a inhibitor of adenylyl cyclase (AC). NKY80 exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values...
NKP-1339, aslo known as IT-139 and KP-1339, is a ruthenium-based anticancer drug in clinical development against...
CAS#: 98636-73-8 (HCl)
Nitrocaramiphen is a muscarinic antagonist with 71-fold selectivity for M1 over M2.
CAS#: 57754-86-6 (HCl)
Nisoxetine hydrochloride is a norepinephrine transporter (NET) inhibitor that inhibits norepinephrine uptake and...
NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ...
Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection
CAS#: 5704-60-9 (HCl)
Nifenalol, also known as INPEA, is a new beta-adrenergic receptor antagonist.
Nicomol is a niacin derivative with antilipidemic activity.
NIBR-189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and...
Nepodin, also know as Musizin; is a naphthol that has been found in Rumex and has diverse biological activities
NED3238 is new highly potent inhibitor of arginase I and II with IC50 values of 1.3 and 8.1 nM, respectively.
NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the...