Fosnetupitant chloride HCl

CAT#: H330229

CAS#: 1643757-72-5

Description: Fosnetupitant is a neurokinin receptor antagonist. Neurokinin 1 (NK1) receptor antagonists (RAs) are a class of drug used to treat nausea and vomiting associated with chemotherapy. Aprepitant, casopitant, and fosaprepitant are NK1 drugs.

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Synthetic Routes

Fosnetupitant chloride HCl - Synthetic Route 1

Fosnetupitant chloride HCl route01

Synthetic reference

Fadini, Luca; Manini, Peter; Pietra, Claudio; Giuliano, Claudio; Lovati, Emanuela; Cannella, Roberta; Venturini, Alessio; Stella, Valentino. (Assignee: Helsinn Healthcare SA, Switz). Substituted 4 - phenyl - pyridines for the treatment of nk-1 receptor related diseases. WO2013082102 (2013).