Ferric maltol

CAT#: H330228

CAS#: 33725-54-1

Description: Ferric maltoll, sold under the brand names Accrufer and Feraccru, is for the treatment of adults with low iron stores. Ferric maltol (ST10): a novel oral iron supplement for the treatment of iron deficiency anemia in inflammatory bowel disease. Ferric maltol is effective in correcting iron deficiency anemia in patients with inflammatory bowel disease: results from a phase-3 clinical trial program. Ferric maltol can cause serious side effects including increased risk of inflammatory bowel disease flare and iron overload in the body.

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Synthetic Routes

Ferric maltol - Synthetic Route 1

Ferric maltol route01

Synthetic reference

Mukha, S. A.; Antipova, I. A.; Medvedeva, S. A.; Saraev, V. V.; Larina, L. I.; Tsyrenzhapov, A. V.; Sukhov, B. G. Synthesis and properties of metal chelates from natural γ-pyrone maltol. Khimiya v Interesakh Ustoichivogo Razvitiya. Volume 15. Issue 4. Pages 457-466. Journal. (2007).

Ferric maltol - Synthetic Route 2

Ferric maltol route02

Synthetic reference

Powell, Jonathan Joseph; Faria, Nuno Jorge Rodrigues. Methods for producing ferric maltol compositions from ferrous hydroxides. Assignee Medical Research Council, UK. WO 2017167970. (2017).

Ferric maltol - Synthetic Route 3

Ferric maltol route03

Synthetic reference

Powell, Jonathan Joseph; Faria, Nuno Jorge Rodrigues. Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides. Assignee Medical Research Council, UK. WO 2017167963. (2017).

Ferric maltol - Synthetic Route 4

Ferric maltol route04

Synthetic reference

Childs, David Paul. Crystalline polymorphic forms of ferric maltol. Assignee Iron Therapeutics Holdings AG, Switz. WO 2016066555. (2016).