Emtricitabine

CAT#: H317769

CAS#:

Description: Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents.

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Synthetic Routes

Emtricitabine - Synthetic Route 1

Emtricitabine route01

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Emtricitabine - Synthetic Route 2

Emtricitabine route02

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Emtricitabine - Synthetic Route 3

Emtricitabine route03

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Emtricitabine - Synthetic Route 4

Emtricitabine route04

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Emtricitabine - Synthetic Route 5

Emtricitabine route05

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Emtricitabine - Synthetic Route 6

Emtricitabine route06

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Emtricitabine - Synthetic Route 7

Emtricitabine route07

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Emtricitabine - Synthetic Route 8

Emtricitabine route08

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Emtricitabine - Synthetic Route 9

Emtricitabine route09

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Emtricitabine - Synthetic Route 10

Emtricitabine route010

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Emtricitabine - Synthetic Route 11

Emtricitabine route011

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Gong, Ping; Wang, Lixin; Wu, Xiujing; Hong, Wei. Synthesis of 2(R)-hydroxymethyl-5(S)-(5'-fluorocytosin-1'- yl)-1,3-oxathiolane (FTC). Zhongguo Yaowu Huaxue Zazhi. School of Pharmaceutical Engineering. Shenyang Pharmaceutical University. Shenyang, Peop. Rep. China 110016. Volume 12. Issue 1. Pages 34-36. 2002.