Pibrentasvir

CAT#: H 528903

CAS#: 1353900-92-1

Description: Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the treatment of HCV infection.

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Synthetic Routes

Pibrentasvir - Synthetic Route 1

Pibrentasvir route01

Synthetic reference

Pibrentasvir - Synthetic Route 2

Pibrentasvir route02

Synthetic reference

Pibrentasvir - Synthetic Route 3

Pibrentasvir route03

Synthetic reference

Pibrentasvir - Synthetic Route 4

Pibrentasvir route04

Synthetic reference

Caspi, Daniel D.; Diwan, Moiz; Califano, Jean-Christophe C.; Mack, Daniel J.; Shekhar, Shashank. Development of an Operational Space Using Mechanistic Models for a Pd-Catalyzed Amidation Reaction Used in the Synthesis of ABT-530. Organic Process Research & Development. Volume 23. Issue 8. Pages 1509-1521. (2019).