WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525086
CAS#: 102671-35-2
Description: FR 64822 is a novel non-opioid antinociceptive compound. It displays antinociceptive activities in a variety of assays with mice and rats. It has a strong antinociceptive activity in the acetic acid writhing test (ED50 = 1.8 mg/kg p.o.).
Hodoodo Cat#: H525086
Name: FR 64822
CAS#: 102671-35-2
Chemical Formula: C11H14N4O
Exact Mass: 218.12
Molecular Weight: 218.260
Elemental Analysis: C, 60.53; H, 6.47; N, 25.67; O, 7.33
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Synonym: FR 64822; FR64822; FR-64822.
IUPAC/Chemical Name: N-(4-Pyridylcarbamoyl)amino 1,2,3,6-tetrahydropyridine
InChi Key: QKXWNCGIAHHUNW-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H14N4O/c16-11(13-10-4-6-12-7-5-10)14-15-8-2-1-3-9-15/h1-2,4-7H,3,8-9H2,(H2,12,13,14,16)
SMILES Code: N(C(=O)Nc1ccncc1)[N@@]1CC=CCC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 218.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Ohkubo Y, Nomura K, Yamaguchi I. Involvement of dopamine in the mechanism of action of FR64822, a novel non-opioid antinociceptive compound. Eur J Pharmacol. 1991 Nov 5;204(2):121-5. PubMed PMID: 1839620.