WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525119
CAS#: 194928-82-0
Description: FR-193879 is a novel, efficacious cephem derivative with extremely potent therapeutic efficacy against H. pylori.
Hodoodo Cat#: H525119
Name: FR-193879
CAS#: 194928-82-0
Chemical Formula: C20H18N4O5S3
Exact Mass: 490.04
Molecular Weight: 490.580
Elemental Analysis: C, 48.97; H, 3.70; N, 11.42; O, 16.31; S, 19.61
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Synonym: FR-193879; FR193879; FR 193879.
IUPAC/Chemical Name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((4-(2-amino-2-oxoethyl)-2-thiazolyl)thio)-8-oxo-7-((2-phenylacetyl)amino)-, (6R,7R)-
InChi Key: YINUFDSCPLNLPS-CRAIPNDOSA-N
InChi Code: InChI=1S/C20H18N4O5S3/c21-13(25)7-11-8-31-20(22-11)32-12-9-30-18-15(17(27)24(18)16(12)19(28)29)23-14(26)6-10-4-2-1-3-5-10/h1-5,8,15,18H,6-7,9H2,(H2,21,25)(H,23,26)(H,28,29)/t15-,18-/m1/s1
SMILES Code: c1ccc(cc1)CC(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)Sc4nc(cs4)CC(=O)N)C(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 490.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Yoshida Y, Matsuda K, Sasaki H, Matsumoto Y, Matsumoto S, Tawara S, Takasugi H. Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879. Bioorg Med Chem Lett. 2004 May 17;14(10):2627-31. PubMed PMID: 15109666.
