WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H121161
CAS#: 117235-10-6
Description: NHS ester is a ProTAC building block. NHS ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protein-polymer conjugates and the synthesis of protein-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use a crosslinking agent, this material can also be used to install functional groups post-polymerization.
Hodoodo Cat#: H121161
Name: NHS ester
CAS#: 117235-10-6
Chemical Formula: C7H9NO4S
Exact Mass: 203.03
Molecular Weight: 203.210
Elemental Analysis: C, 41.37; H, 4.46; N, 6.89; O, 31.49; S, 15.78
Synonym:
IUPAC/Chemical Name: 3-Mercaptopropanyl-N-hydroxysuccinimide ester
InChi Key: UTBOEPMMEANMPS-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
SMILES Code: SCCC(ON1C(CCC1=O)=O)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 203.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
