WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122043
CAS#: N/A
Description: D-Amino-PEG6-Thalidomide TFA salt is comprised of an amine group linked to ?-Phthalimidoglutarimide through PEG6. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Thalidomide group is useful in PROTAC research and often referred to as dBET1 as a powerful BRD4 degrader.
Hodoodo Cat#: H122043
Name: D-Amino-PEG6-Thalidomide TFA salt
CAS#: N/A
Chemical Formula: C27H39N3O10
Exact Mass: 565.26
Molecular Weight: 565.620
Elemental Analysis: C, 57.33; H, 6.95; N, 7.43; O, 28.29
Synonym: D-Amino-PEG6-Thalidomide TFA salt
IUPAC/Chemical Name: 2-(1-(20-amino-3,6,9,12,15,18-hexaoxaicosyl)-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChi Key: SBCVQPNTHBDMCS-UHFFFAOYSA-N
InChi Code: InChI=1S/C27H39N3O10/c28-7-9-35-11-13-37-15-17-39-19-20-40-18-16-38-14-12-36-10-8-29-24(31)6-5-23(27(29)34)30-25(32)21-3-1-2-4-22(21)26(30)33/h1-4,23H,5-20,28H2
SMILES Code: O=C1N(C2C(N(CCOCCOCCOCCOCCOCCOCCN)C(CC2)=O)=O)C(C3=CC=CC=C31)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 565.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |