WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122021
CAS#: 2112737-93-4
Description: DSPE-PEG5-propargyl is a PEG linker with attached DSPE and propargyl groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The hydrophilic PEG linker increases the water solubility of the compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
Hodoodo Cat#: H122021
Name: DSPE-PEG5-propargyl
CAS#: 2112737-93-4
Chemical Formula: C55H104NO14P
Exact Mass: 1,033.72
Molecular Weight: 1,034.400
Elemental Analysis: C, 63.86; H, 10.13; N, 1.35; O, 21.65; P, 2.99
Synonym: DSPE PEG5 propargyl, PEG5 propargyl, PEG5 propargyl,
IUPAC/Chemical Name: (2R)-3-((hydroxy((4-oxo-7,10,13,16,19-pentaoxa-3-azadocos-21-yn-1-yl)oxy)phosphoryl)oxy)propane-1,2-diyl distearate
InChi Key: TWBDHVREIJJEGS-OIVUAWODSA-N
InChi Code: InChI=1S/C55H104NO14P/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-54(58)67-50-52(70-55(59)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-5-2)51-69-71(60,61)68-41-38-56-53(57)37-40-63-43-45-65-47-49-66-48-46-64-44-42-62-39-6-3/h3,52H,4-5,7-51H2,1-2H3,(H,56,57)(H,60,61)/t52-/m1/s1
SMILES Code: CCCCCCCCCCCCCCCCCC(OC[C@@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCOCCOCCOCCOCCOCC#C)=O)(O)=O)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 1,034.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |