WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122206
CAS#: N/A
Description: Pomalidomide-PEG5-Azide, I is a PROTAC linker that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.Azide enable click chemistry with Alkyne, DBCO or BCN molecules.
Hodoodo Cat#: H122206
Name: Pomalidomide-PEG5-Azide
CAS#: N/A
Chemical Formula: C26H34N6O10
Exact Mass: 590.23
Molecular Weight: 590.590
Elemental Analysis: C, 52.88; H, 5.80; N, 14.23; O, 27.09
Synonym: Pomalidomide-PEG5-Azide
IUPAC/Chemical Name: 1-azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12,15-pentaoxaoctadecan-18-amide
InChi Key: TZOHJKYEXIATGQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H34N6O10/c27-31-28-7-9-39-11-13-41-15-17-42-16-14-40-12-10-38-8-6-22(34)29-19-3-1-2-18-23(19)26(37)32(25(18)36)20-4-5-21(33)30-24(20)35/h1-3,20H,4-17H2,(H,29,34)(H,30,33,35)
SMILES Code: O=C1NC(C(N2C(C3=C(NC(CCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)C=CC=C3C2=O)=O)CC1)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
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The following data is based on the product molecular weight 590.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |