WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122233
CAS#: N/A
Description: GL67 is a cationic lipid composed of cholesterol coupled to spermine. GL67 may be used to mediate gene transfer into mammalian cells. This lipid was a critical component for successfully completed clinical studies in the delivery of pDNA via inhalation.
Hodoodo Cat#: H122233
Name: GL67
CAS#: N/A
Chemical Formula: C38H70N4O2
Exact Mass: 614.55
Molecular Weight: 615.000
Elemental Analysis: C, 74.21; H, 11.47; N, 9.11; O, 5.20
Synonym: LF47XVU5BD; N4-Spermine cholesterol carbamate
IUPAC/Chemical Name: (3S,10R,13R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-aminopropyl)(4-((3-aminopropyl)amino)butyl)carbamate
InChi Key: KBBLYWGVXTZWCU-FWAFJIPTSA-N
InChi Code: InChI=1S/C38H70N4O2/c1-28(2)11-8-12-29(3)33-15-16-34-32-14-13-30-27-31(17-19-37(30,4)35(32)18-20-38(33,34)5)44-36(43)42(26-10-22-40)25-7-6-23-41-24-9-21-39/h13,28-29,31-35,41H,6-12,14-27,39-40H2,1-5H3/t29-,31+,32?,33-,34?,35?,37+,38-/m1/s1
SMILES Code: NCCCNCCCCN(CCCN)C(O[C@@H]1CC2=CCC(C(CC[C@@H]3[C@H](C)CCCC(C)C)[C@]3(C)CC4)C4[C@@]2(C)CC1)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 615.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |