SST0116CL1

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H130014

CAS#: N/A

Description: SST0116CL1 is a heat shock protein 90 inhibitor that inhibits tumor growth by binding to the ATP pocket of Hsp90, interfering with the function of the chaperone of Hsp90. SST0116CL1 has been shown to have the potential to be a candidate for use in cancer therapy.

Chemical Structure

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SST0116CL1
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H130014
Name: SST0116CL1
CAS#: N/A
Chemical Formula: C22H31ClN4O6
Exact Mass: 482.19
Molecular Weight: 482.962
Elemental Analysis: C, 54.71; H, 6.47; Cl, 7.34; N, 11.60; O, 19.88

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: SST0116CL1

IUPAC/Chemical Name: 5-(2,4-Dihydroxy-5-isopropyl-phenyl)-N-ethyl-4-(3-morpholinopropanoylamino)isoxazole-3-carboxamide

InChi Key: IJBIOWMKHRRFCS-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H30N4O6.ClH/c1-4-23-22(30)20-19(24-18(29)5-6-26-7-9-31-10-8-26)21(32-25-20)15-11-14(13(2)3)16(27)12-17(15)28;/h11-13,27-28H,4-10H2,1-3H3,(H,23,30)(H,24,29);1H

SMILES Code: O=C(C1=NOC(C2=CC(C(C)C)=C(O)C=C2O)=C1NC(CCN3CCOCC3)=O)NCC.Cl

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 482.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Vesci L, Milazzo FM, Carollo V, Pace S, Giannini G. Preclinical antitumor activity of SST0116CL1: a novel heat shock protein 90 inhibitor. Int J Oncol. 2014 Oct;45(4):1421-9. doi: 10.3892/ijo.2014.2575. Epub 2014 Aug 1. PMID: 25096516; PMCID: PMC4151799.