WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130033
CAS#: 2495096-26-7
Description: Lartesertib, also known as M4076, is a serine and threonine kinase inhibitor and has potential for application as an antineoplastic agent.
Hodoodo Cat#: H130033
Name: Lartesertib
CAS#: 2495096-26-7
Chemical Formula: C23H21FN6O3
Exact Mass: 448.17
Molecular Weight: 448.460
Elemental Analysis: C, 61.60; H, 4.72; F, 4.24; N, 18.74; O, 10.70
Synonym: Lartesertib; M4076; M-4076; M 4076,; ATM Inhibitor-5; EX-A6943;
IUPAC/Chemical Name: 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
InChi Key: WNEFOSMCGCLLJU-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H21FN6O3/c1-12-15(11-28(2)27-12)13-6-14-17(7-19(13)32-4)26-9-18-21(14)30(23(31)29(18)3)22-16(24)8-25-10-20(22)33-5/h6-11H,1-5H3
SMILES Code: O=C(N1C2=C(F)C=NC=C2OC)N(C)C3=C1C4=CC(C5=CN(C)N=C5C)=C(OC)C=C4N=C3
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 448.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |