WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130048
CAS#: 2392951-29-8
Description: Relutrigine is a sodium channel blocker.
Hodoodo Cat#: H130048
Name: Relutrigine
CAS#: 2392951-29-8
Chemical Formula: C15H11F6N5O2
Exact Mass: 407.08
Molecular Weight: 407.280
Elemental Analysis: C, 44.24; H, 2.72; F, 27.99; N, 17.20; O, 7.86
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Synonym: Relutrigine
IUPAC/Chemical Name: 3-(ethoxydifluoromethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)pyridin-3-yl][1,2,4]triazolo[4,3-a]pyrazine
InChi Key: BFXBSYMVTNEFRF-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H11F6N5O2/c1-2-28-15(20,21)13-25-24-11-5-22-10(6-26(11)13)8-3-9(16)12(23-4-8)27-7-14(17,18)19/h3-6H,2,7H2,1H3
SMILES Code: FC(F)(F)COC1=C(F)C=C(C2=CN3C(C=N2)=NN=C3C(F)(OCC)F)C=N1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Sodium channel blockers are often used as therapeutic treatments for conditions such as cardiac arrhythmias, epilepsy, neurodegenerative diseases, cancer, spasticity, chronic and neuropathic pain.
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 407.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Zuliani V, Rapalli A, Patel MK, Rivara M. Sodium channel blockers: a patent review (2010 - 2014). Expert Opin Ther Pat. 2015 Mar;25(3):279-90. doi: 10.1517/13543776.2014.995628. Epub 2014 Dec 24. PMID: 25539043.