AzoFPP-1

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Hodoodo CAT#: H130095

CAS#: N/A

Description: AzoFPP-1 is a photoswitchable analog of farnesyl diphosphate that has been shown to allow for effective optical control of substrate prenylation by farnesyltransferase. Furthermore, this process has been the first successful case of transforming isoprenoid lipid into a photolipid. Photoswitchable lipids show promise in optically controlling lipid bioactivity, metabolism, and biophysical properties.

Chemical Structure

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AzoFPP-1
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H130095
Name: AzoFPP-1
CAS#: N/A
Chemical Formula: C17H17N2Na3O8P2
Exact Mass: 508.02
Molecular Weight: 508.250
Elemental Analysis: C, 40.17; H, 3.37; N, 5.51; Na, 13.57; O, 25.18; P, 12.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: AzoFPP-1; AzoFPP1; AzoFPP 1

IUPAC/Chemical Name: Sodium (E)-3-methyl-4-(3-((E)-phenyldiazenyl)phenoxy)but-2-en-1-yl diphosphate

InChi Key: MNOKLVGNGVARAO-PNTIMCPCSA-K

InChi Code: InChI=1S/C17H20N2O8P2.3Na/c1-14(10-11-26-29(23,24)27-28(20,21)22)13-25-17-9-5-8-16(12-17)19-18-15-6-3-2-4-7-15;;;/h2-10,12H,11,13H2,1H3,(H,23,24)(H2,20,21,22);;;/q;3*+1/p-3/b14-10+,19-18+;;;

SMILES Code: O=P([O-])(OP([O-])([O-])=O)OC/C=C(C)/COC1=CC=CC(/N=N/C2=CC=CC=C2)=C1.[Na+].[Na+].[Na+]

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 508.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Morstein J, Bader T, Cardillo AL, Schackmann J, Ashok S, Hougland JL, Hrycyna CA, Trauner DH, Distefano MD. Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation. ACS Chem Biol. 2022 Oct 21;17(10):2945-2953. doi: 10.1021/acschembio.2c00645. Epub 2022 Oct 4. PMID: 36194691; PMCID: PMC9799063.