WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130106
CAS#: N/A
Description: UV blocker A33 is a photoprotective agent against skin photoageing caused by exposure to UV-B rays. A33 specifically, had significant protective effects at 10 μM and 25 μM against UV-B (10 mJ/cm2) -induced damage in HDFs, and at 25 μM was found to actively prevent collagen degradation and restore some of the UV-B induced damage.
Hodoodo Cat#: H130106
Name: UV blocker A33
CAS#: N/A
Chemical Formula: C38H51FO5
Exact Mass: 606.37
Molecular Weight: 606.820
Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 75.21; H, 8.47; F, 3.13; O, 13.18
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: UV blocker A33
IUPAC/Chemical Name: (2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bR)-11-((E)-2-Fluoro-4-methoxybenzylidene)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
InChi Key: PQYZELFDIFTGAC-DMDLLLTPSA-N
InChi Code: InChI=1S/C38H51FO5/c1-33(2)29-11-12-38(7)30(36(29,5)20-23(31(33)41)17-22-9-10-24(44-8)18-27(22)39)28(40)19-25-26-21-35(4,32(42)43)14-13-34(26,3)15-16-37(25,38)6/h9-10,17-19,26,29-31,41H,11-16,20-21H2,1-8H3,(H,42,43)/b23-17+/t26-,29-,30+,31-,34+,35-,36-,37+,38+/m0/s1
SMILES Code: O=C([C@](CC[C@]1(C)CC[C@@]2(C)[C@]3(C)CC[C@@]4([H])C(C)(C)[C@@H](O)/C(C[C@]4(C)[C@]35[H])=C/C6=CC=C(OC)C=C6F)(C)C[C@@]1([H])C2=CC5=O)O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 606.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1. Kumar A, Archo S, Singh CP, Naikoo SH, Singh B, Kaur S, Tasduq SA. Photoprotective effect of 18β-glycyrrhetinic acid derivatives against ultra violet (UV)-B-Induced skin aging. Bioorg Med Chem Lett. 2022 Nov 15;76:128984. doi: 10.1016/j.bmcl.2022.128984. Epub 2022 Sep 24. PMID: 36167293.
