SIR1-365

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H122753

CAS#: N/A

Description: SIR1-365 is a RIPK 1inhibitor

Chemical Structure

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SIR1-365
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H122753
Name: SIR1-365
CAS#: N/A
Chemical Formula: C13H17F2NO2
Exact Mass: 257.12
Molecular Weight: 257.280
Elemental Analysis: C, 60.69; H, 6.66; F, 14.77; N, 5.44; O, 12.44

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: SIR1-365; SIR1365; SIR 1365

IUPAC/Chemical Name: N-(3,5-difluorobenzyl)-N-hydroxy-2,2-dimethylbutanamide

InChi Key: SQPMQJPGOUAGHC-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H17F2NO2/c1-4-13(2,3)12(17)16(18)8-9-5-10(14)7-11(15)6-9/h5-7,18H,4,8H2,1-3H3

SMILES Code: CCC(C)(C)C(N(CC1=CC(F)=CC(F)=C1)O)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 257.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Alba GA, Ziehr DR, Rouvina JN, Hariri LP, Knipe RS, Medoff BD, Hibbert KA, Kowal A, Hoenstine C, Ginns LC, Lewis GD, Hardin CC. Exercise performance in patients with post-acute sequelae of SARS-CoV-2 infection compared to patients with unexplained dyspnea. EClinicalMedicine. 2021 Aug 28;39:101066. doi: 10.1016/j.eclinm.2021.101066. PMID: 34476393; PMCID: PMC8401400.