WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130178
CAS#: 74606-99-8
Description: Lansine is an anti-TB and HIV agent and has potential to treat leishmaniases.
Hodoodo Cat#: H130178
Name: Lansine
CAS#: 74606-99-8
Chemical Formula: C14H11NO3
Exact Mass: 241.07
Molecular Weight: 241.246
Elemental Analysis: C, 69.70; H, 4.60; N, 5.81; O, 19.90
This product is not in stock, which may be available by custom synthesis.
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Synonym: Lansine
IUPAC/Chemical Name: 2-hydroxy-6-methoxy-9H-carbazole-3-carbaldehyde
InChi Key: INFFNJXOAJWVCS-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H11NO3/c1-18-9-2-3-12-11(5-9)10-4-8(7-16)14(17)6-13(10)15-12/h2-7,15,17H,1H3
SMILES Code: O=CC1=CC2=C(C=C1O)NC3=C2C=C(OC)C=C3
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 241.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Pieroni M, Girmay S, Sun D, Sahu R, Tekwani BL, Tan GT. Synthesis and structure-activity relationships of lansine analogues as antileishmanial agents. ChemMedChem. 2012 Nov;7(11):1895-900. doi: 10.1002/cmdc.201200346. Epub 2012 Sep 17. PMID: 22987791; PMCID: PMC3565020.
2. Ma C, Case RJ, Wang Y, Zhang HJ, Tan GT, Van Hung N, Cuong NM, Franzblau SG, Soejarto DD, Fong HH, Pauli GF. Anti-tuberculosis constituents from the stem bark of Micromelum hirsutum. Planta Med. 2005 Mar;71(3):261-7. doi: 10.1055/s-2005-837826. PMID: 15770548; PMCID: PMC2940840.