Welcome to Hodoodo Chemicals

Moracin C
new

featured

WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H330095

CAS#: 69120-06-5

Description: Moracin C is a phenolic compound isolated from Artocarpus heterophyllus. Moracin C suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages. Moracin C has been proven to exhibit inhibitory activities against lipoxygenase enzymes, TNF-α and interleukin-1β secretion, and proprotein convertase subtilisin/kexin type 9 expression.

Chemical Structure

Moracin C

CAS# 69120-06-5

Instruction

Theoretical Analysis

Hodoodo Cat#: H330095
Name: Moracin C
CAS#: 69120-06-5
Chemical Formula: C19H18O4
Exact Mass: 310.12
Molecular Weight: 310.349
Elemental Analysis: C, 73.53; H, 5.85; O, 20.62

Price and Availability

Size	Price	Availability
10mg	USD 950	2 Weeks
25mg	USD 1450	2 Weeks
50mg	USD 2450	2 Weeks
100mg	USD 3850	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. Hodoodo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Moracin C;

IUPAC/Chemical Name: 1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)-2-(3-methyl-2-buten-1-yl)-

InChi Key: ZTGHWUWBQNCCOH-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H18O4/c1-11(2)3-6-15-16(21)7-13(8-17(15)22)18-9-12-4-5-14(20)10-19(12)23-18/h3-5,7-10,20-22H,6H2,1-2H3

SMILES Code: OC1=CC(C2=CC3=CC=C(O)C=C3O2)=CC(O)=C1C/C=C(C)\C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 310.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Parise A, De Simone BC, Marino T, Toscano M, Russo N. Quantum Mechanical Predictions of the Antioxidant Capability of Moracin C Isomers. Front Chem. 2021 Apr 21;9:666647. doi: 10.3389/fchem.2021.666647. PMID: 33968905; PMCID: PMC8097241.

2: Masagalli JN, BasavanaGowda MK, Chae HS, Choi WJ. Synthesis of Moracin C and Its Derivatives with a 2-arylbenzofuran Motif and Evaluation of Their PCSK9 Inhibitory Effects in HepG2 Cells. Molecules. 2021 Mar 2;26(5):1327. doi: 10.3390/molecules26051327. PMID: 33801308; PMCID: PMC7958322.

3: You BH, BasavanaGowda MK, Lee JU, Chin YW, Choi WJ, Choi YH. Correction: Pharmacokinetic Properties of Moracin C in Mice. Planta Med. 2021 Feb 5. doi: 10.1055/a-1384-8484. Epub ahead of print. Erratum for: Planta Med. 2021 Jan 26;: PMID: 33545721.

4: You BH, BasavanaGowda MK, Lee JU, Chin YW, Choi WJ, Choi YH. Pharmacokinetic Properties of Moracin C in Mice. Planta Med. 2021 Jul;87(8):642-651. doi: 10.1055/a-1321-1519. Epub 2021 Jan 26. Erratum in: Planta Med. 2021 Feb 05;: PMID: 33498088.

5: Li X, Xie H, Zhan R, Chen D. Effect of Double Bond Position on 2-Phenyl- benzofuran Antioxidants: A Comparative Study of Moracin C and Iso-Moracin C. Molecules. 2018 Mar 24;23(4):754. doi: 10.3390/molecules23040754. PMID: 29587376; PMCID: PMC6017532.

6: Yao X, Wu D, Dong N, Ouyang P, Pu J, Hu Q, Wang J, Lu W, Huang J. Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages. Int J Mol Sci. 2016 Jul 25;17(8):1199. doi: 10.3390/ijms17081199. PMID: 27463712; PMCID: PMC5000597.

7: Kim YJ, Sohn MJ, Kim WG. Chalcomoracin and moracin C, new inhibitors of Staphylococcus aureus enoyl-acyl carrier protein reductase from Morus alba. Biol Pharm Bull. 2012;35(5):791-5. doi: 10.1248/bpb.35.791. PMID: 22687419.

Your view history

Moracin C new featured