WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525551
CAS#: 26766-37-0
Description: LY 56110 is a novel class of nonsteroidal aromatase inhibitor.
Hodoodo Cat#: H525551
Name: LY 56110
CAS#: 26766-37-0
Chemical Formula: C17H12Cl2N2
Exact Mass: 314.04
Molecular Weight: 315.200
Elemental Analysis: C, 64.78; H, 3.84; Cl, 22.49; N, 8.89
This product is not in stock, which may be available by custom synthesis.
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Synonym: LY 56110; LY-56110; LY56110.
IUPAC/Chemical Name: Pyrimidine, 5-(bis(4-chlorophenyl)methyl)-
InChi Key: FOQIAMHLCXUKND-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H12Cl2N2/c18-15-5-1-12(2-6-15)17(14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,17H
SMILES Code: ClC1=CC=C(C(C2=CN=CN=C2)C3=CC=C(Cl)C=C3)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
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The following data is based on the product molecular weight 315.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: O'Neill LA, Geisert RD, Zavy MT, Morgan GL, Wettemann RP. Effect of estrogen inhibitors on conceptus estrogen synthesis and development in the gilt. Domest Anim Endocrinol. 1991 Jan;8(1):139-53. PubMed PMID: 2013219.
2: Hirsch KS, Jones CD, Lindstrom TD, Stamm NB, Sutton GP, Taylor HM, Weaver DE. Discovery and development of a novel class of nonsteroidal aromatase inhibitors. Steroids. 1987 Jul-Sep;50(1-3):201-17. PubMed PMID: 3504060.
3: Lindstrom TD, Whitaker GW. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987 May;8(4):595-604. PubMed PMID: 3609545.