WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122986
CAS#: 328250-28-8
Description: Also known as 1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride). It is a cationic lipid and the more immunologically active isomer of DOTAP.
Hodoodo Cat#: H122986
Name: R-DOTAP
CAS#: 328250-28-8
Chemical Formula: C42H80ClNO4
Exact Mass: 697.58
Molecular Weight: 698.560
Elemental Analysis: C, 72.22; H, 11.54; Cl, 5.07; N, 2.01; O, 9.16
Synonym: 1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride); R-DOTAP
IUPAC/Chemical Name: (R)-N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride
InChi Key: KSXTUUUQYQYKCR-HEXDFCBFSA-M
InChi Code: InChI=1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;/t40-;/m1./s1
SMILES Code: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-]
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 698.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |