WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130367
CAS#: 1643841-88-6
Description: APN-Azide is a bifunctional crosslinker allowing for the coupling of thiol to alkyne.
Hodoodo Cat#: H130367
Name: APN-Azide
CAS#: 1643841-88-6
Chemical Formula: C9H4N4
Exact Mass: 168.04
Molecular Weight: 168.159
Elemental Analysis: C, 64.28; H, 2.40; N, 33.32
Synonym: APN-Azide; APN-N3
IUPAC/Chemical Name: 3-(4-azidophenyl)propiolonitrile
InChi Key: BDLXITYEYYHQNK-UHFFFAOYSA-N
InChi Code: InChI=1S/C9H4N4/c10-7-1-2-8-3-5-9(6-4-8)12-13-11/h3-6H
SMILES Code: N#CC#CC1=CC=C(N=[N+]=[N-])C=C1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 168.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Kolodych S, Koniev O, Baatarkhuu Z, Bonnefoy JY, Debaene F, Cianférani S, Van Dorsselaer A, Wagner A. CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability. Bioconjug Chem. 2015 Feb 18;26(2):197-200. doi: 10.1021/bc500610g. Epub 2015 Jan 23. PMID: 25614935.