WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130357
CAS#: N/A
Description: C5 Lenalidomide-benzyl-piperazine HCl is a key component in the synthesis of molecules for targeted protein degradation and PROTAC research. It is composed of a Cereblon (CRBN)-recruiting ligand, a rigid linker, and a pendant amine that reacts with the carboxylic acid on the target ligand.
Hodoodo Cat#: H130357
Name: C5 Lenalidomide-benzyl-piperazine HCl
CAS#: N/A
Chemical Formula: C25H28ClN5O4
Exact Mass: 0.00
Molecular Weight: 497.980
Elemental Analysis: C, 60.30; H, 5.67; Cl, 7.12; N, 14.06; O, 12.85
Synonym: C5 Lenalidomide-benzyl-piperazine HCl; C5 Lenalidomide-benzyl-piperazine hydrochloride
IUPAC/Chemical Name: N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)-4-(piperazin-1-ylmethyl)benzamide hydrochloride
InChi Key: FYDHHUZWYCJEBY-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H27N5O4.ClH/c31-22-8-7-21(24(33)28-22)30-15-18-13-19(5-6-20(18)25(30)34)27-23(32)17-3-1-16(2-4-17)14-29-11-9-26-10-12-29;/h1-6,13,21,26H,7-12,14-15H2,(H,27,32)(H,28,31,33);1H
SMILES Code: O=C(NC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)C4=CC=C(CN5CCNCC5)C=C4.[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 497.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |