WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130365
CAS#: N/A
Description: C5 Lenalidomide-C9-NH2 HCl is a building block in the synthesis of protein degraders and PROTACs, containing a (CRBN)-recruiting ligand with an alternative exit vector and a PEGylated crosslinker whose pendant amine reacts with an acid on the target warhead.
Hodoodo Cat#: H130365
Name: C5 Lenalidomide-C9-NH2 HCl
CAS#: N/A
Chemical Formula: C23H33ClN4O4
Exact Mass: 0.00
Molecular Weight: 464.990
Elemental Analysis: C, 59.41; H, 7.15; Cl, 7.62; N, 12.05; O, 13.76
Synonym: C5 Lenalidomide-C9-NH2 hydrochloride; C5 Lenalidomide-C9-NH2 HCl
IUPAC/Chemical Name: 10-amino-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)decanamide hydrochloride
InChi Key: CZHMMBPCMVKJOU-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H32N4O4.ClH/c24-13-7-5-3-1-2-4-6-8-20(28)25-17-9-10-18-16(14-17)15-27(23(18)31)19-11-12-21(29)26-22(19)30;/h9-10,14,19H,1-8,11-13,15,24H2,(H,25,28)(H,26,29,30);1H
SMILES Code: O=C(NC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)CCCCCCCCCN.[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 464.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |