WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130371
CAS#: N/A
Description: EMCH, also known as N-(ε-maleimidocaproic acid) hydrazide, trifluoroacetic acid salt, is a crosslinker that is membrane permeable, water soluble, and contains a 6-carbon spacer arm bound by a maleimide group and hydrazide group. The maleimide group reacts with sulfhydryl, forming stable thiol ether bonds at pHs of 6.5-7.5, while the hydrazide group reacts with carbonyl.
Hodoodo Cat#: H130371
Name: EMCH
CAS#: N/A
Chemical Formula: C12H16F3N3O5
Exact Mass: 0.00
Molecular Weight: 339.271
Elemental Analysis: C, 42.48; H, 4.75; F, 16.80; N, 12.39; O, 23.58
Synonym: EMCH; N-(ε-maleimidocaproic acid) hydrazide, trifluoroacetic acid salt
IUPAC/Chemical Name: N-(ε-maleimidocaproic acid) hydrazide, trifluoroacetic acid salt
InChi Key: DRURMGRBAVYWCL-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H15N3O3.C2HF3O2/c11-12-8(14)4-2-1-3-7-13-9(15)5-6-10(13)16;3-2(4,5)1(6)7/h5-6H,1-4,7,11H2,(H,12,14);(H,6,7)
SMILES Code: O=C(C=C1)N(CCCCCC(N[NH3+])=O)C1=O.[O-]C(C(F)(F)F)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 339.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |